Awesome pairs of people I'd like to see fight to the death:

R.L. Stine vs. Kelsey Grammar
Albus Dumbledore vs. Jonathan Lipnicki
George Orwell vs. Pippi Longstocking
Superman vs. Emily Dickinson
Tommy Pickles vs. Burt Bacharach
Hillary Clinton vs. a possessed Trapper Keeper
New York City vs. Linda Hunt
Della Reese vs. Mothra